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A 41-year-old female asked:

many people say positive ana means nothing as many people without lupus can have that. why is it done to screen for lupus then- if it means nothing?

1 doctor answer1 doctor weighed in
Dr. Gurmukh Singh
Pathology 49 years experience
Titer: If ANA is detected only in serum diluted to about 40 fold, it does not mean a whole lot. However, if it still present after the serum has been diluted 160 fold, it does mean auto-immune response. In other words, the strength of ANA matters. Visit this site for more info. http://www.mayoclinic.org/tests-procedures/ana-test/basics/definition/PRC-20014566

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Last updated Sep 8, 2015

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