My husband has stage 4 nsclc with mets to bone and liver adreanal glands chemo is no longer effective. what options are left?

Tertiary care: I would make sure your husband is being cared for at an advance tertiary care center with a focus on onc. There are several different chemo regimens available, and even though cure is not the goal improved quality an length of life may be possible.

Difficult: Comfort care and pain control. It sounds like you have had the oncologist do all they know. Family and friends close by.