Staph infection: I believe the most common explanation is a staph infection...the most common bacteria living on your skin. The thigh is a common place due to friction of your legs rubbing together, reducing the skin's natural resistance to infection, causing a boil. They tend to recur and may be prevented with use of the skin cleanser 2% chlorhexadine and/or a course of the anti-staph antibiotic erythromycin.
Answered 7/23/2016
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