A member asked:

The interaction between klonopin (clonazepam) and tegretol:tegretol lowers klonopin (clonazepam) by 30% -does klonopin (clonazepam) raise tegretol ?

A doctor has provided 1 answer

Not great combo: Concomitant administration of clonazepam (Klonopin) and carbamazepine (Tegretol) resulted in a 22% increase in clonazepam clearance and a 20.5% decrease in carbamazepine clearance. Carbamazepine is well known to induce its own metabolism as well as the metabolism of other meds making it difficult to manage. Consult provider. Bottom line - Klonopin is not likely to raise Tegretol levels.

Answered 6/19/2015

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