A 49-year-old male asked:
Why does tegretol reduce the effectiveness of klonopin (clonazepam) by 30% but not ativan?
1 doctor answer • 5 doctors weighed in
Psychiatry 43 years experience
Klonopin (clonazepam) vs Ativan: Tegretol induces the metabolism of drugs which are metabolized by the liver enzyme cyp 3a4. Klonopin (clonazepam) is one of these drugs, but Ativan is not. This means that in the presence of tegretol, Klonopin (clonazepam) may be metabolized faster than expected, reducing its effectiveness.
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4.4k viewsReviewed >2 years ago
Last updated Apr 17, 2016
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