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A member asked:
What do you think if a person has a consistently high c4 complement? ccp, ana+, hla b27+ (no inflammatory arthritis). occasional elevated cr; fatigue
4 doctors weighed in across 2 answers
Not to worry: Thee is no disease associated with a high c4. Patients with active lupus may have a low c4. Your other results are confusing. Sounds like you need a rheumatologist to do a complete history and physical exam and to interpret the results of the lab studies.
Answered 7/4/2015
5.2k views
Not true.: C4 is a marker for inflammation, and unless consumed by complement mediated cell damage, such as in sle, it is an acute phase reactant and is elevated in RA and ankylosing spondylitis. Both are common disease. I have 8 patients with both! you probably have both as and ra!
Answered 6/10/2014
5.1k views
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