A member asked:

18-year old w joint pain and fatigue for 10 yrs. diagnosed with sle/psa. hydroxychloroquine for 2 yrs then salazopyrine + leflunomide - no effect. ana + at 1/320, c4 low, high ferritin, anti-tg+. looking for tests that might help correct diagnosis?

A doctor has provided 1 answer
Dr. Pierre Moeser answered

Specializes in Rheumatology

You clearly have an inflammatory disorder. Assuming antiTG is antiThyroglobulin, you may have an overlap with Hashimoto thyroiditis. ANA is positive in this condition. Ask your rheumatologist if he/she has done any highly specific lupus testing such as anti-Smith, double-stranded DNA. Don't be afraid to ask; you are trying to understand your condition.

Answered Jan 26, 2023

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