A member asked:

18-year old w joint pain and fatigue for 10 yrs. diagnosed with sle/psa. hydroxychloroquine for 2 yrs then salazopyrine + leflunomide - no effect. ana + at 1/320, c4 low, high ferritin, anti-tg+. looking for tests that might help correct diagnosis?

A doctor has provided 1 answer

You clearly have an inflammatory disorder. Assuming antiTG is antiThyroglobulin, you may have an overlap with Hashimoto thyroiditis. ANA is positive in this condition. Ask your rheumatologist if he/she has done any highly specific lupus testing such as anti-Smith, double-stranded DNA. Don't be afraid to ask; you are trying to understand your condition.

Answered 1/26/2023

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