A member asked:

What causes gout?

6 doctors weighed in across 3 answers

Crystal deposition: Uric acid precipitates out as a crystal and irritates white blood cells, producing inflammation.

Answered 4/2/2013

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Deposition of : Uric acid in the joints. Too much uric acid secondary to overproduction or underexcretion.

Answered 4/15/2013

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High Uric Acid: High levels of uric acid in the blood. High uric acid levels 'hyperuricemia' don't always cause symptoms, however when these levels cause crystals to develop and sit in a joint (often the big toe joint), this causes an acute gout episode. Alcohol, red meat, shellfish, certain medications, among other things, may all increase risk. Diagnosis based on removing joint fluid and looking for crystals.

Answered 4/4/2013

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