A member asked:

My 17 y-o softball player daughter has mono. know about spleen risk. clarify fully recovered/when she can return. 2 weeks in and fatigue only symptom.

2 doctors weighed in across 2 answers
Dr. Tony Ho answered

Specializes in Internal Medicine

Should be safe: Most symptoms, including the splenomegaly, resolve by 2 weeks, which is generally considered the 'safe to resume normal activities" time frame. The fatigue, as you've noticed, tends to persist; it can last for a few months, without any other symptoms.

Answered 11/5/2015

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May be fine now: You can always have her pcp evaluate her for an enlarged spleen ( physical exam ) and at this point if it never enlarged or is returning to normal size there would be minimal risk. Be aware that playing through fatigue places her at some increased risk of injury do to decline in vigilance.Some caution is reasonable until she is feeling up to her normal level.

Answered 3/29/2013

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