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A member asked:
I know alzheimer's can be caused by excess dopamine, and adhd by not enough dopamine... so if i take adderall (dextroamphetamine and racemic amphetamine) for adhd, am i at risk of alzheimer's?
9 doctors weighed in across 4 answers
AD neurotransmitters: Ad is more complicated that a simple neurotransmitter imbalance. Communication between brain cells is compromised in ad, dopamine, acetylcholine and glutamate all have a role to play. While some cortical pathways are shared in add and ad, one does not necessarily increase the risk of the other. Maximally treating your add including non-drug therapy is critical to maintaining a healthy brain.
Answered 6/9/2015
5.2k views
Probably not: The current theories of ad emphasize reduced synthesis of the neurotransmitter acetylcholine along with amyloid plaques & neurofibrillary tangles inside nerve cells that disrupt neural functioning. Ad individuals also lose locus coeruleus cells that generate norepinephrine. Other theories suggest possible inflammatory and glutamatergic roles. Parkinson's is assoc'd w/ Dopamine loss, not ad.
Answered 11/28/2017
5.2k views
Not related: Alzheimer's disease is not related to Dopamine as far as is known.
Answered 6/25/2014
5.2k views
No correlation: Alzheimer's is due to a combination of many different factors but excess Dopamine is not one of them. There is no correlation or known risk between taking Adderall (dextroamphetamine and racemic amphetamine) and developing alzheimer's.
Answered 6/25/2014
5.2k views
Related Questions
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