A member asked:

Is it possible or probable that the drug adderall, (dextroamphetamine and racemic amphetamine) if used long-term, could cause eventual dopamine depletion?

A doctor has provided 1 answer

No evidence: Amphetamines have been used therapeuticly for over 90 years. There is no evidence of depletion of dopamine brain stores from the therapeutic use.

Answered 6/18/2018

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