With a family history of lupus and 7 out of 11 symtoms, can you still have lupus if after 2 positive ana and anti dna you have a negitive result?

Are you on treatment: If on treatment, dna-ds antibody titers can bnormalize. You would be considered "in remission, " but because you are on rx. If I have patients with disease sx and positive serologies, i would place them on plaquenyl. Tests can normalize, even with this simple rx! also, immune disease activity can remit on its own!

No: Anti da-dna and or anti smith antibody need to be positive to make the diagnosis, .

Yes: I agree with dr. Namey on this issue. I would not disregard the previously positive tests even if the current studies are negative. Have you seen a rheumatologist?