A 32-year-old female asked:
With a family history of lupus and 7 out of 11 symtoms, can you still have lupus if after 2 positive ana and anti dna you have a negitive result?
3 doctor answers • 5 doctors weighed in

Dr. Thomas Nameyanswered
Rheumatology 50 years experience
Are you on treatment: If on treatment, dna-ds antibody titers can bnormalize. You would be considered "in remission, " but because you are on rx. If I have patients with disease sx and positive serologies, i would place them on plaquenyl. Tests can normalize, even with this simple rx!
also, immune disease activity can remit on its own!
Created for people with ongoing healthcare needs but benefits everyone.
5.2k viewsReviewed >2 years ago

Dr. Eneida Agosto-Colonanswered
Rheumatology 32 years experience
No: Anti da-dna and or anti smith antibody need to be positive to make the diagnosis, .
Created for people with ongoing healthcare needs but benefits everyone.
5.2k viewsAnswered >2 years ago

A Verified Doctoranswered
Rheumatology 54 years experience
Yes: I agree with dr. Namey on this issue. I would not disregard the previously positive tests even if the current studies are negative. Have you seen a rheumatologist?
Created for people with ongoing healthcare needs but benefits everyone.
5.2k viewsReviewed >2 years ago
Last updated Dec 10, 2013
People also asked
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $44!
50% off with $15/month membership
Disclaimer:
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.