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A member asked:

Can you be diagnosed with lupus if you have only positive ana and symptoms? even if dna was negative..?

A doctor has provided 1 answer
Dr. Silviu Pasniciuc answered

Specializes in Internal Medicine

Yes: You may have lupus in the absence of a positive anti DNA antibody test. Among other possibilities you may suffer from seronegative lupus. In time the test may become positive.

Dr Arnold agreed

Answered 11/27/2014

3.5k views

Thank

Related Questions

A member asked:

Diagnosed w/lupus 10 years ago &have been on plaqunenil. For past 6 years, my SED rate, c3, c4, and crp have been normal.my double stranded dna has been always negative. I have Ana 1:640 and other qualifying symptoms. Do I no longer have lupus ?

A doctor has provided 1 answer

A member asked:

I had some blood test done and I have and blood test call ANA which was positive with a 1:1280 titre and ANA (homogenous pattern had a negative DNA and ENA also had raised ESR and raised monocytes What diagnosis could this be Lupus does run in family?

2 doctors weighed in across 2 answers

A member asked:

I had a biopsy for localized Discoid Lupus. It came back positive. Blood work shows 1:80 ANA, negative for DS-DNA and negative for SM Antibody. Should I be concerned that I also have SLE?

2 doctors weighed in across 2 answers

A member asked:

Lupus or RA? Positive ANA 1:160, Speckled, Homogeneous; Neg ENA, Anti-DNA, & RF; High ESR, CRP, Ab IgG, 14-3-3 eta, & Leukocyte Esterase; Low Lymphocy

A doctor has provided 1 answer

A member asked:

Hi there, I have sjgrens syndrome and mild lupus but my double strand DNA was neg, my ANA was 1:640 with speckled pattern. How can it be mild lupus?

3 doctors weighed in across 2 answers

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People also searched for:

I had a negative ANA test but positive double stranded DNA test do I have lupus?
Neg ana. Anti ds DNA indeterminate (value 6) 0-4 neg, 5-9 indeterminate, 10+ pos. All other labs normal. Possible lupus? No real other symptoms.
Does ANA 1:320 with symptoms indicate lupus even if the DNA was neg and SM was low? RF neg and CCP neg.
I had a positive ANA of 1:40 Nucleolar pattern and an anti DS DNA come back high at 6 along with multiple Lupus symptoms. Does this mean I have Lupu?
Lupus or no? I have strange symptoms so my doc decided to test me for autoimmune disease. Two years ago everything was negative. Last week, Ana was negative but ds dna test was intermediate. 4 below is neg, 5-9 is intermediate. Mine is 6

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