Denton, MD
A 30-year-old female asked:
I had a positive ana, double stranded dna, and i believe smith's antibodies. i also had a butterfly rash at the time. besides lupus, what could it be?
2 doctor answers • 5 doctors weighed in
Dr. SG Ermananswered
Family Medicine 37 years experience
Not Much: Sounds pretty diagnostic for lupus to me.
Created for people with ongoing healthcare needs but benefits everyone.
6.1k viewsReviewed >2 years ago
Dr. SG Erman commented
Family Medicine 37 years experience
Provided original answer
Absolutely. The rash of lupus is usually not really bumpy. This could be something else, especially if your lab work is totally normal
Jan 30, 2012
Dr. Randy Burgettanswered
General Practice 11 years experience
Probably Lupus: A butterfly rash is often seen with lupus, but could also been seen with vitamin deficiency disorders like pellagra or connective tissue disases like dermatomyositis. However, the positive ANA and smith's antibodies most likely indicate it is lupus. You should see your physician to be properly diagnosed.
Created for people with ongoing healthcare needs but benefits everyone.
6.1k viewsReviewed >2 years ago
Dr. Randy Burgett commented
General Practice 11 years experience
Provided original answer
Did these antibodies only test positive once? There may have been a false positive reading. Also, I think Smith antibodies may disappear with treatment, although Lupus cannot be cured. If your rheumy said its not Lupus, it may be a connective tissue disorder. I would follow up with him or another physician.
Jan 30, 2012
Last updated Oct 24, 2017
People also asked
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $44!
50% off with $15/month membership
Disclaimer:
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.