A member asked:

Can you have ankylosing spondylitis with a negative antibody blood test?

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Yes: The common arthritis labs are usually negative in ankylosing sponcylitis.

Answered 7/11/2016

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Not usually.: There are always false negatives and positives. There are other tests to help confirm the diagnosis . A good rheumatologist will be able to help.

Answered 7/11/2016

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Yes: While most people with spondylitis carry the genetic marker called hla b-27, it is not present in 10-20% of spondylitis patients. In that situation, the diagnosis is made by finding typical x-ray, ct or MRI changes in the sacro-iliac joints. Likewise, only 20% of people who carry the b-27 gene ever develop spondylitis or a related condition.

Answered 7/11/2016

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