What is an effective medicine for apical lung nodule?

Depends: Depends on what the nodule is? First you need appropriate diagnosis. This is best by a multidiscipline comprehensive thoracic surgical lung nodule program. If the nodule is a tumor, treatment will depend on type and staging if malignant.

Removal: If an infection is proven then medicines can help: tuberculosis, pneumonia, histoplasmosis etc. If the nodule is cancer, most likely removal is the best option depending on other risk factors and lung capacity.