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Malvern, PA
A 22-year-old female asked:

What does a variation in results for ana blood test in the past all were negative what does it mean if the titer is 1:80 and a speckled pattern ?

2 doctor answers4 doctors weighed in
Dr. Darrell Herrington
Family Medicine 36 years experience
Not much: You need tests for specific antibodies in order to diagnose an auto-immune inflammatory condition such as lupus. See your doctor for complete evaluation. ANA has a high incidence of false positives.
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Dr. Theresa Yang
Dr. Theresa Yanganswered
General Practice 11 years experience
Autoimmune disease: ANA is a marker for autoimmune diseases like lupus and rheumatoid arthritis. A <1:80 titer is low, meaning there is a lower chance of disease. A "speckled pattern" refers to the staining pattern of the markers, which is seen under the microscope. Certain autoimmune diseases produce specific staining patterns. A negative ANA means you do not have that marker of disease.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Sep 18, 2018

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