U.S. doctors online nowAsk doctors free
Ossining, NY
A 34-year-old female asked:

My 1st trimester screening came back very low 1 in 3, 000. i just took the harmony genetic test. is there any chance my risk can change to high risk?

2 doctor answers2 doctors weighed in
Dr. Jeff Livingston
Obstetrics and Gynecology 23 years experience
Possible but likely: Harmony is testing fetal dna thus giving a much more accurate result. First trimester screening is a good test but works differently. It tests your hormone levels along with a sonographic measurement of the fetal neck. These are different technologies to assess risk.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Phillip Shubert
37 years experience
Not likely: Your numbers are quite good. The 1 in 3000 is based on your first trimester screen which is a probability. The harmony test is based on the fetal dna in your blood. Therefore, it has a higher detection rate than the first trimester screen, and in theory could change--but not highly likely given your good numbers.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jan 31, 2015


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.