U.S. doctors online nowAsk doctors free
Ossining, NY
A 34-year-old female asked:

I had a normal first trimester screening and harmony prenatal test. is an afp blood test necessary? can it come back high risk?

2 doctor answers2 doctors weighed in
Dr. Barbara Coulter-Smith
33 years experience
It is different.: First trimester screens and the harmony test are for chromosomal abnormalities. The AFP tests for neural tube defects (spina bifida).
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Jie Xu
Dr. Jie Xuanswered
Obstetrics and Gynecology 18 years experience
The msAFP is: To assess the risk of open neural tube defects i.e. Spina bifida, which is not tested by harmony or the first trimester screen. It is up to you if you would like to be screened for ntds. Keep in mind that, if detected, these defects can be repaired by a skilled pediatric neurosurgeon while the baby is still inside you. Speak to your obgyn and make an informed decision. Hope this helps.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jan 31, 2015

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.