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A 34-year-old female asked:

I had a normal first trimester screening and harmony prenatal test. is an afp blood test necessary? can it come back high risk?

2 doctor answers • 2 doctors weighed in
Dr. Barbara Coulter-Smith
Dr. Barbara Coulter-Smithanswered
34 years experience
It is different.: First trimester screens and the harmony test are for chromosomal abnormalities. The AFP tests for neural tube defects (spina bifida).
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Dr. Jie Xu
Dr. Jie Xuanswered
Obstetrics and Gynecology 19 years experience
The msAFP is: To assess the risk of open neural tube defects i.e. Spina bifida, which is not tested by harmony or the first trimester screen. It is up to you if you would like to be screened for ntds. Keep in mind that, if detected, these defects can be repaired by a skilled pediatric neurosurgeon while the baby is still inside you. Speak to your obgyn and make an informed decision. Hope this helps.
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5.3k viewsAnswered >2 years ago
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Last updated Jan 31, 2015

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