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A 33-year-old female asked:

Which is a better predictor of down syndrome during the first trimester screening, low papp-a or high hcg levels? or the ratio between the two values?

1 doctor answer1 doctor weighed in
Dr. Gurmukh Singh
Pathology 50 years experience
Four tests: A combination of four tests, quad screen, is done twice as a screening test for down syndrome. See this site for more info. http://www.mayoclinic.com/health/quad-screen/my00127.
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Last updated Jun 30, 2021

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