Is methotrexate has to be taken life long for ra is the only available option? if yes means , what are chronic complications of taking methotrexate?

No there are many: Option, your dodctor will be to chose the best option for you. Dry cough, shortness of breath; diarrhea, vomiting, white patches or sores inside your mouth or on your lips; blood in your urine or stools; urinating less than usual or not at all; fever, chills, body aches, flu symptoms; sore throat and headache with a severe blistering, peeling, and red skin rash; pale skin, easy bruising and others.