In your opinion, for the best chance of a successful iui how many mature follicles should you have at trigger? i'm 41 years old with an fsh of 7.7

3 or 4: On average at age 41 we would want you to have about 3-4 mature follicles. That is because on average about 50% of eggs at age 40 are genetically abnormal and so the assumption is that with 4 eggs likely 2 will be capable of producing a health baby. Too many increase the chances of multiples.

5 to 6: Although we usually aim for 2-4 follicles in patients int their 30 s, i would aim for more in a patient that is 41. The data from pgs in patients doing ivf shows that 90% of embryos can be abnormal. This explains the 50% moscarriage rate in women over 40. Ultimately more eggs is better in a 41 year old so ivf may be best choice as the rate of multiples can be controlled by # for et.