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A member asked:

Can you explain what this might mean: "apparent polyclonal gammopathy: igm. kappa and lambda increased". immunoglobulin m is also high at 437.?

3 doctors weighed in across 2 answers
Dr. Michael Dugan answered

Specializes in Hematology

Monoclonal processes: Are often malignant or pre malignant. Polyclonal processes are usually reactive/infectious/inflammatory.

Dr Kandarpa agreed

Answered 8/5/2020

5.4k views

Thank

Infection: These results likely indicate a recent infection but need to be evaluated in the context of other laboratory tests and your exam.

Answered 5/3/2019

5.4k views

Thank

Related Questions

A member asked:

Can a monclonal IgM kappa light chain gammopathy turn into macrogobulinemia-waldenstrom?

A doctor has provided 1 answer

A member asked:

I am 45 and male. Serum IgA at 472 mg/dl and an apparent polyclonal gammopathy IgA kappa/lambda typing appear increased. Serum free light chain: high kappa 35 mg/L, lambda normal 17.8 mg/L and a ratio of 1.97. Is this Myeloma? No M-protein found?

A doctor has provided 1 answer

A member asked:

An apparent polyclonal gammopathy: IgA. Kappa and lambda typing appear increased. What does this mean? Im being referred to a Hematologist, Do I have Cancer?

2 doctors weighed in across 2 answers

A member asked:

What would cause free kappa &free lamba to be high but ratio normal also Immunoglobulin M, Qn, Serum high. platelets steady rising & WBC high for 1yr?

2 doctors weighed in across 2 answers

A member asked:

Kappa/lambda FLC ratio high (2.75) w/ normal K(10.21mg/dl) & low L(3.68mg/dl). Hem-onc unsure if ratio implies K monoclonality since serum/urine IFE ok & neither chain is elevated. Could monoclonal K be suppressing L? IgA a bit high IgG &IgM a bitlow

5 doctors weighed in across 2 answers

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