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A 44-year-old female asked:

What would cause free kappa &free lamba to be high but ratio normal also immunoglobulin m, qn, serum high. platelets steady rising & wbc high for 1yr?

2 doctor answers2 doctors weighed in
Dr. Donald Colantino
Internal Medicine 62 years experience
Hematologist: A hematologist is best qualified to answer your question. Your findings suggest monoclonal spike in the electrophoresis and some sort of bone marrow proliferative disorder.
Dr. Saptarshi Bandyopadhyay
Hospital-based practice 22 years experience
Polyclonal gammopath: Something is stimulating all the B cell lines to produce a lot of antibodies. That general condition is called polyclonal gammopathy. It can be caused by a chronic infection (virus) or 9 other broad categories of causes (liver problems, connective tissue diseases, bone marrow disorder like Waldenstrom's, drugs/meds, autoimmune probs, misc). It's too much to go into here. Use Healthtap Prime to tal
Last updated May 26, 2016


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