A 56-year-old male asked:
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been diagnosed with peripheral neuropathy blood test showed high immunoglobulin m w/polyclonal gammopathy. kappa/lambda increase. possible meaning?

2 doctor answers
Dr. Carlo Valencia
15 years experience Internal Medicine
PlasmaCellDIsorder: May have plasma cell disorder/multiple myeloma. Plasma cells are a type of white blood cells that produces immunoglobulin(antibodies). Multiple myeloma is a cancerous or excessive proliferation of these plasma cells which may lead to excessive high levels of calcium/bone pain/renal failure/anemia (low blood counts). Need to see hematologist (blood doctor specialist).
Answered on Feb 4, 2020
Dr. Bruce Rothschild
47 years experience Rheumatology
Hyperactive immune: Hyperactive immune system, but no specific meaning.
Answered on Nov 17, 2013

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Dr. Michael Dugan
Specializes in Hematology
Monoclonal processes: Are often malignant or pre malignant. Polyclonal processes are usually reactive/infectious/inflammatory.
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A 40-year-old female asked:
Dr. Gurmukh Singh
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Need more info: The information you provided is insufficient for a meaningful opinion. Do you have any symptoms? All laboratory results need to be interpreted in the ... Read More
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Dr. Martin Raff
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Labs: Cannot possibly interpret lab results in the absence of a medical history and exam. If you have had these tests ordered by a doctor, discuss results ... Read More
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Dr. Olav Jaren
18 years experience Neurology
Try urology: traumatic nerve injury would not respond to IVIG treatment. For your particular condition, a urologist could probably help.

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