Been prescribed 15mg mirtazapine, worried about grogginess. will half dose make me less groggy the next day? i very sensitive to side effects. thanks

Most Likely not: Everyone has different reactions to different medications, but Mirtazapine is different - it makes most people groggy at lower doses, and less so at higher doses, paradoxically. You should consult with your doctor just to be sure - as it would be a disservice to you if i said anything more without more information about your condition.

Try it: There is some argument that lower mrtazepine causes increased sedation..However I have seen the opposite. Higher dosage cuases more sedation esp. In the elderly. Try it and you will be your best doctor to feel it. It is not going to hurt you to cut down the dosage anyway.

Remeron (mirtazapine): Agree with my colleagues but recommend working closely with your doc.

Unique: A unique property of Mirtazapine is that it tends to be more sedating and anxiolytic at lower doses (ie. 15mg) compared with higher doses (30mg, 45mg). I haven't found this to be necessarily true at 7.5mg. However, if there are concerns about sedation, you should usually start with the lowest dose possible and titrate as needed. Don't drive or perform crucial activities before you know how you will respond.

Remeron (mirtazapine): As my colleagues mentioned, it is best to discuss with your prescribing doc. Before making any changes.

Individualized: Remeron (mirtazapine) affects two neurotransmitter systems cooperatively for its main effect, but sometimes in opposite ways with respect to side effects! depending on your own personal responsiveness (very hard to anticipate) lowering the dose may decrease or increase the grogginess you describe. It may also pass. Best to discuss with your physician and possibly experiment under his/her guidance.