Does the grogginess of mirtazapine wear off the longer you take it? many thanks.

Yes: And the same goes for any psychiatric meds sedation effect. Mirtazrepine gives you a desired weight gain and good sleep effect. Another plus is minimal sexual side effects with this one same as wellbuterin..

Often: Sedation is a common side effect of mirtazepine. In us trials for depression 54% percent reported this as a side effect. 10.4% of individuals in the trials stopped the medication as a result as opposed to about 2.2% on placebo. So you can figure about 80% of the time the sedation was mild enough or resolved quickly enough for the patient to stick with the medication. Please consult your physician.