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A 35-year-old member asked:

Is clozapine ever used for treating chronic pain?

3 doctor answers6 doctors weighed in
Dr. Ron Jones
Family Medicine 45 years experience
Maybe: I personally do not use anti-psychotics for pain management. I could not say that it is never used, as I am sure some docs use this and other anti-psychotics for pain management, but this is not the indication for the drug.
Dr. Richard Williams
Pharmacy 18 years experience
Not usually: It is more common in chronic pain to add specific classes of antidepressants to the treatment. Clozapine is a 2nd generation antipsychotic not an antidepressant. Discuss this possibility with your physician.
Dr. Heidi Fowler
Psychiatry 25 years experience
Clozapine: Although atypical antipsychotics have reportedly been tried for chronic pain, I don't know anyone who does this. Clozaril (for schizophrenia) has possible serious side effects & requires rigid monitoring. I don't think it would be a wise choice. REF: https://www.clinicalpainadvisor.com/home/topics/chronic-pain/atypical-antipsychotics-as-adjuncts-in-chronic-pain-management-how-effective-are-they

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Last updated Jan 9, 2021

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