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A 35-year-old member asked:

Is clozapine ever used for treating chronic pain?

3 doctor answers6 doctors weighed in
Dr. Ron Jones
Family Medicine 47 years experience
Maybe: I personally do not use anti-psychotics for pain management. I could not say that it is never used, as I am sure some docs use this and other anti-psychotics for pain management, but this is not the indication for the drug.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Richard Williams
Pharmacy 20 years experience
Not usually: It is more common in chronic pain to add specific classes of antidepressants to the treatment. Clozapine is a 2nd generation antipsychotic not an antidepressant. Discuss this possibility with your physician.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Heidi Fowler
Psychiatry 27 years experience
Clozapine: Although atypical antipsychotics have reportedly been tried for chronic pain, I don't know anyone who does this. Clozaril (for schizophrenia) has possible serious side effects & requires rigid monitoring. I don't think it would be a wise choice. REF: https://www.clinicalpainadvisor.com/home/topics/chronic-pain/atypical-antipsychotics-as-adjuncts-in-chronic-pain-management-how-effective-are-they
Created for people with ongoing healthcare needs but benefits everyone.

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Last updated Jan 9, 2021

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