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A 22-year-old female asked:

Im 26 weeks pregnant, i broke out in hives last week, will a lot of benedryl/ zyrtec and cortizone (hydrocortisone) creams affect my unborn baby? my hives burn...

1 doctor answer2 doctors weighed in
Dr. Joram Seggev
Specializes in Internal Medicine - Allergy & Immunology
Probably not: Zyrtec is a class b (very safe), Benadryl (diphenhydramine) is category c (safe). Odds are that your baby will be fine. However, simple hives usually itch, not burn. If you need to use a lot of medication without getting adequate relief, go see your obstetrician and/or a dermatologist.
Last updated Dec 19, 2015


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