What does a cystoscopy feel like?

A procedure.: Cystoscopies are uncomfortable but most patients tolerate them well. Usually, a numbing gel is placed in the urethra. The initial entry of the scope is the most uncomfortable part, where it passes beyond the urethral sphincter. Irrigating fluid will enter your bladder to aid in visualization, which will feel like a fullness to the bladder. After the procedure, discomfort rapidly subsides.