A member asked:

Do the antidepressants zoloft and/or wellbutrin (bupropion) make vyvanse less effective?

5 doctors weighed in across 2 answers
Dr. Alan Ali answered

Specializes in Psychiatry

Zoloft (sertraline): Not likely. Combination used often.

Answered 5/31/2018

5.7k views

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No: Neither zoloft or wellbutrin (bupropion) should interfere with the therapeutic efficacy of vyvanse.

Answered 4/13/2016

5.6k views

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