A member asked:

What exactly is dent's disease?

A doctor has provided 1 answer

Genetic disorder: Dent's disease is an x-linked recessive disorder of the proximal renal tubules characterized by hypercalciuria, nephrocalcinosis, kidney stones, renal failure, and rickets. The specific mutation involves inactivation of a voltage-gated chloride transporter.

Answered 8/12/2012

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