A member asked:

Have clinical trials ever shown that ldl reduction prevents cad or death?

2 doctors weighed in across 2 answers

Yes: Clinical trials with drugs that lower LDL have shown a reduction, not elimination, of cad.

Answered 7/15/2012

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Dr. Milton Alvis, jr answered

Specializes in Preventive Medicine

Yes, essentiall ALL: Starting with trials in the early 1970s & becoming far more dramatic since 1995 (4-s trial using zocor (simvastatin) was reported 1995), essentially all clinical trials showing reduction of either LDL particles (most reliable, see: NMR particle test) or estimated ldl-cholesterol, have shown reductions in all cause mortality, mostly due to cv events plus a trend to lower cancer rates. >30 human clinical trials.

Answered 6/10/2014

5.4k views

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