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A 40-year-old member asked:

How does abilify (aripiprazole) work?

2 doctor answers4 doctors weighed in
Dr. Alan Ali
Dr. Alan Alianswered
Psychiatry 33 years experience
Abilify (aripiprazole): Abilify (aripiprazole) is partial Dopamine agonist (some increase in dopamine) plus serotonin antagonist, both of which cause some agitation & sweating.
Dr. Robert Woods
Psychiatry 31 years experience
Good Question: The exact mechanism by which Abilify (aripiprazole) (generic aripiprizole) works is unknown. We know that Abilify (aripiprazole) selectively binds different receptors based upon dose. At low doses it treats depression by binding serotonin. At high doses it treats schizophrenia by binding dopamine. While these binding affinities are well documented, there may be other undiscovered mechanisms of action. Stay tuned!

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A 30-year-old member asked:

Does Abilify (aripiprazole) work well for schizophrenia?

2 doctor answers7 doctors weighed in
Dr. Andrew Ho
Psychiatry 31 years experience
Very well: For some, less for others. Like most psychiatric medications, hard to predict until you try it.
A 30-year-old member asked:

Does Abilify (aripiprazole) work both as an antidepressant and an antimanic?

1 doctor answer3 doctors weighed in
Dr. Alan Ali
Dr. Alan Alianswered
Psychiatry 33 years experience
Abilify (aripiprazole): At proper dosages, yes.
A 32-year-old member asked:

Could Abilify (aripiprazole) work as an antidepressant alone?

2 doctor answers3 doctors weighed in
Dr. Jane Steiner
Psychiatry 44 years experience
Sometimes...: Sometimes Abilify (aripiprazole) works well enough as an antidepressant that one can take it alone.
Iran
A 21-year-old male asked:

How could Abilify (aripiprazole) work for unipolar TRDepression?

1 doctor answer1 doctor weighed in
Dr. Anthony Vita
Specializes in Psychiatry
IT IS NOT CLEAR: The mechanism of aripiprazole (Abilify) is not exactly known. However, it seems to enhance the effects of dopamine and serotonin when these are low.

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Last updated Dec 24, 2017

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