A 39-year-old member asked:
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why is it bad to use a nasal spray with oxymetazoline hydrochloride nightly?

1 doctor answer
Dr. Patrick Melder
26 years experience ENT and Head and Neck Surgery
Tachyphylaxis: Basically your nose will become desentized to the effect of the oxymetazoline. If you use beyond the recommend time (3-5 days), your nose will upregulate receptors for it and require more and more for the same effect. There are better options for nightly nasal stuffiness and simple in-office procedures can be a permanent solution for you - see your local ent.
Answered on Nov 12, 2018
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Related questions:

A 42-year-old member asked:
Dr. Michael Zacharisen
32 years experience Allergy and Immunology
Yes, short term: Oxymetazoline is a nasal decongestant spray that works quickly to decrease stuffy nose, but if used beyond 4-7 days may result in "rebound" nasal cong ... Read More
A 41-year-old member asked:
Dr. Neil Giddings
38 years experience ENT and Head and Neck Surgery
No: It should not be used on a daily basis.
1
1 thank
A 38-year-old member asked:
Dr. James Beckman
50 years experience Plastic Surgery
Limit use of spray: Use this nasal spray only every 12 hours or so to prevent "rebound dryness" and refractory congestion.
5
5 thanks
A 48-year-old member asked:
Dr. Anifat Balogun
28 years experience ENT and Head and Neck Surgery
Yes: Oxymetazoline should only be used for 3 to 5 days maximum. See your doctor if you still have significant nasal congestion after this time period.

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