A member asked:

Why is it bad to use a nasal spray with oxymetazoline hydrochloride nightly?

A doctor has provided 1 answer

Tachyphylaxis: Basically your nose will become desentized to the effect of the oxymetazoline. If you use beyond the recommend time (3-5 days), your nose will upregulate receptors for it and require more and more for the same effect. There are better options for nightly nasal stuffiness and simple in-office procedures can be a permanent solution for you - see your local ent.

Answered 11/12/2018

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