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A 20-year-old male asked:

why do the mitochondria in people with acromegaly not work as well, since growth hormone makes mitochondria work better?

1 doctor answer1 doctor weighed in
Dr. Lois Freisleben-Cook
Pediatrics 41 years experience
Investigation: continues into the mechanism of impaired production of ATP in acromegaly. Hypothesis include long term effects of increased GH on insulin sensitivity, increased utilization of fatty acids with subsequent impairment due to accumulation of by products of fatty acid metabolism and unspecified problems with energy flux. Some of these seem to persist even after treatment of acromegaly.

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Similar questions

A 33-year-old member asked:

With acromegaly, what is done to block the growth hormone?

1 doctor answer1 doctor weighed in
Dr. Soumya Adhikari
Pediatric Endocrinology 20 years experience
A few options: Many people with acromegaly have a tumor of their pituitary gland, and thus benefit from surgery as part of their treatment. Medications to assist in the management are also available, either to help decrease the production of excess growth hormone (octreotide, for ex.) or to block its effects (pegvisomant). This can be a serious problem, and something one should see a specialist for.
Topton, PA
A 43-year-old female asked:

If someone is told they have an excess of growth hormone does that mean they have acromegaly? Or are there other conditions or issues that it can be?

1 doctor answer1 doctor weighed in
Dr. Michael Kleerekoper
A Verified Doctor answered
A US doctor answered Learn more
Growth hormone : Excess growth hormone is unlikely at your age. Are you being treated for hypothyroidism? Has a doctor prescribed vitamins, probiotics, etc? If so, your doctor should carefully review what meds you need.

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Last updated Dec 13, 2014

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