A member asked:

My fertility doctor required my egg donor to get a cmv test. the results came back "reactive" to igg (nonreactive to igm). can we still use her eggs for ivf?

5 doctors weighed in across 3 answers
Dr. James Rochester answered

Specializes in Family Medicine

Are you CMV+: Would want to know if you are CMV+ or -. CMV is a viral infection most of us acquire as a child and never know it. Discuss with your fertility specialist the importance esp if you are CMV - and donor CMV+. If you are both CMV+ I do not know of any issue, but again discuss with your fertility specialist. Hope this helps. Best of luck trying to conceive. Dr R

Answered 2/3/2015

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Dr. Johanna Fricke answered

Specializes in Pediatrics - Developmental and Behavioral

Yes, if her CMV IgG : titer is stable over time. A + test for CMV IgG shows she was infected with CMV at some time during her life, but doesn't tell you when. If antibody tests of paired serum samples show a 4 x increase in CMV IgG antibody & CMV IgM antibody is present or CMV virus is cultured from her urine or throat, then she has an active infection. Your CMV IgG may show you're protected.

Answered 2/3/2015

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Dr. Duane Gels answered

Specializes in Allergy and Immunology

CMV & donor eggs: This means the egg donor was exposed to CMV (though not recently), and in theory, and might reappear during gestation: very harmful to the fetus. Whether or not this eliminates this donor is controversial; it's a decision made together with your fertility specialist. Issue is how likely reactivation will occur. At 46, if you are the gestational mom, pregnancy is already high risk. Discuss w/ doc.

Answered 2/3/2015

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