Multiple sclerosis -- is there loss of use of hands?

Multiple sclerosis: Inflamation attack on myelin covering nerves can attack any group of neuron so could give motor problems like loss of use of limbs.

Yes: Weakness as well as coordination problems can happen.

On occasion: Most often, only one arm is severely afflicted, and other relatively spared, if therapy fails to blunt or stop progression. The key item, is to take potent effective meds such as Tysabri (natalizumab) or Gilenya, as the ultimate goal is to avoid disability, and prevent transition to the secondary progressive phase.