A member asked:

When zoloft and lexapro loose their efficacy and one cannot take paxil (paroxetine) because of weight gain what other ssri possibilities are there for anx and dep

A doctor has provided 1 answer

SNRIs: There are many possibilities. SNRIs which are cousins of SSRIs w/ a norepinephrine component can be equally or more efficacious than SSRIs w/ sometimes less side effects such as weight gain & sexual dysfunction - would suggest evaluation w/ your Physician to discuss appropriate options

Answered 1/21/2015

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