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Turlock, CA
A 23-year-old female asked:

Im currently taking mastic gum and dgl. im planning on doing urea breath test for h pylori in a few weeks. will these supplements interfere the test?

2 doctor answers3 doctors weighed in
Dr. Randy Baker
Holistic Medicine 40 years experience
Not exactly but...: Mastic gum is an effective treatment for H. pylori so hopefully it will eliminate H. pylori overgrowth from your stomach. Thus, taking it should significantly reduce the chance of the test being positive. In that sense it may "interfere" with the test by curing you before the test, but won't result in inaccurate results. If the test is still positive it will suggest you need additional treatment.
Dr. Yoshimasa Makino
Gastroenterology 19 years experience
I must politely disagree here. If the mastic gum kills some but not all of the H pylori, this may result in a "false negative" test. In other words, the test may state you don't have H pylori but in fact you still do.
Sep 3, 2014
Dr. Randy Baker
Dr. Randy Baker commented
Holistic Medicine 40 years experience
Provided original answer
You may have a good point Dr. Makino. The labs state there is a possibility of a false negative if you have been on antimicrobials within 2 weeks of the test & thus advise stopping antimicrobials & proton pump inhibitors 2 weeks prior to testing. But it can be argued that if the level of H. pylori antigens are so low they can't be detected that the remaining few may not be clinically significant.
Sep 3, 2014
Dr. Yoshimasa Makino
Gastroenterology 19 years experience
Best to stop them...: While the data on mastic gum and DGL is limited, and while the American Gastroenterological Association does not endorse them as treatments for H pylori, they can potentially interfere with the test. If the mastic gum kills some but not all of the H pylori, this may result in a "false negative" test. In other words, the test may state you don't have H pylori but in fact you still do.

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Last updated Sep 9, 2014

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