A member asked:

Good idea to be taking melatonin and benadryl (diphenhydramine) together for an inability to sleep?

A doctor has provided 1 answer
Dr. Michael Rupp answered

Specializes in Allergy and Immunology

Not Really: It is always dangerous to mix multiple sedating medications especially if you drink alcohol or take pain medication or other sedatives. In addition, prolonged use of Benadryl (diphenhydramine) for sleep can cause poor quality sleep due to disruption of resting brain wave patterns. Best to stick with Melatonin. See a sleep specialist if your insomnia does not improve.

Answered 9/1/2014

3.8k views

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