A 40-year-old member asked:
How does sulfasalazine measure up to other 5-asa drugs such as asacol (mesalamine) and colazal for ulcerative colitis?
2 doctor answers • 2 doctors weighed in

Dr. Thomas Nameyanswered
Rheumatology 49 years experience
SFZ vs Asacol (mesalamine): Sfz is the best drug for intestinal disease, certainly "1" for regional enteritis and crohn's in the si. However, colonic bacteria breaks down sfz, and Asacol (mesalamine) is not. So for large bowel disease Asacol (mesalamine) is preferred for reasons of efficacy.
5.8k viewsReviewed >2 years ago
1 comment

A Verified Doctor commented
A US doctor answered Learn more
These are all effective for mild ulcerative colitis. None of them have long-term benefit for crohn's disease (aka regional enteritis).
Nov 24, 2012

A Verified Doctoranswered
28 years experience
Similar for UC: These are all fairly effective for mild ulcerative colitis. None of them have long-term benefit for crohn's disease (aka regional enteritis).
5.5k viewsAnswered >2 years ago
Last updated May 3, 2016
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