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A 40-year-old member asked:

How does sulfasalazine measure up to other 5-asa drugs such as asacol (mesalamine) and colazal for ulcerative colitis?

2 doctor answers2 doctors weighed in
Dr. Thomas Namey
Rheumatology 49 years experience
SFZ vs Asacol (mesalamine): Sfz is the best drug for intestinal disease, certainly "1" for regional enteritis and crohn's in the si. However, colonic bacteria breaks down sfz, and Asacol (mesalamine) is not. So for large bowel disease Asacol (mesalamine) is preferred for reasons of efficacy.
Dr. Jeremy Adler
A Verified Doctor commented
A US doctor answered Learn more
These are all effective for mild ulcerative colitis. None of them have long-term benefit for crohn's disease (aka regional enteritis).
Nov 24, 2012
Dr. Jeremy Adler
A Verified Doctoranswered
28 years experience
Similar for UC: These are all fairly effective for mild ulcerative colitis. None of them have long-term benefit for crohn's disease (aka regional enteritis).
Last updated May 3, 2016

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