how does sulfasalazine measure up to other 5-asa drugs such as asacol (mesalamine) and colazal for ulcerative colitis?

Question

Is asacol (mesalamine) a good treatment for ulcerative colitis flare-ups, or is it only useful to stay in remission?

Answer 1

SFZ vs Asacol (mesalamine): Sfz is the best drug for intestinal disease, certainly "1" for regional enteritis and crohn's in the si. However, colonic bacteria breaks down sfz, and Asacol (mesalamine) is not. So for large bowel disease Asacol (mesalamine) is preferred for reasons of efficacy.

Answer 2

Similar for UC: These are all fairly effective for mild ulcerative colitis. None of them have long-term benefit for crohn's disease (aka regional enteritis).

Answer 3

Aspirin: My personal opinion is aspirin. Still have to worry about stomach upset and ulcers. Getting positive cardiac effects plus pain relief.

Answer 4

Both are antiinflamm: Both are anti-inflammatory and there are better ways to reduce systemic inflammation. Start w/ your food - follow anti-inflammatory diet (low in refined foods, sugar, etc, high in veggies & fruits). Add omega-3 fatty acids. Anti-inflammatory herbs include turmeric, ginger, rosemary. Combo product is zyflamend. Stress reduction also lowers inflammation. All take time & improve health overall.

Answer 5

Esophagus? GB? other: Could be esophageal inflammation or spasm, gallbladder disease, pancreatic disease, colon issues, other. Check for other stuff. Sono safe, painless, no xray screen for gallbladder, liver issues see your doc.

Answer 6

Gallbladder: Chronic cholecystitis or biliary dyskinesia... Need a gb u/s first, then if negative, a hida scan...

Answer 7

Right treatment: Most important step is accurate diagnosis! if an md has confirmed pain comes from an ulcer & determined the kind, treatment likely included antibiotics (if the bacteria called h. Pylori was present) + a proton pump inhibitor (e.g., omeprazole) to reduce acid. If your ulcer didnt heal, other problems will need to be looked for, so it is important to let the treating doctor know. Do not handle alone.

Answer 8

Ulcers: Ulcers are typically treated with proton pump inhibitors such as omeprazole. If you have them occurring frequently, you need to see your doctor to get checked for h. Pylori and have a scope done to check for other problems. Contrary to myth, alcohol and spicy foods will not affect ulcers, however they will affect esophageal reflux. See your doctor as soon as possible.

Answer 9

See below: Stomach ulcers, like any other tissue injury, will heal on its own. Ulcers don't last 5 years. Ulcers should heal withing 2 months and if not have a high risk for being cancerous. Most who are told they have ulcers, (without an endoscopy to prove it) don't have ulcers. If you have persistent pain for 5 years you need to see your doctor and have an endoscopic evaluation.

Answer 10

Aspirin: Can cause bleeding. I would have an eye doctor check it out.

Answer 11

Yes and no: Aspirin interferes with blood clotting mechanisms. Therefore immediately after a fall if there is any suspicion of active bleeding it should not be used along with other agents, such as ibuprofen. After a fall with resulting in hip pain i would be concerned with impending hip fracture versus muscular trauma which requires a thorough examination. If there is no danger adult dosage may be used.

how does sulfasalazine measure up to other 5-asa drugs such as asacol (mesalamine) and colazal for ulcerative colitis?

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