My doc changed my tramadol from 50mg to 100 mg i took 100 mg at 545 pm can i take another 100 mg at 1145pm ! i know max dose is 400 per day doc said!

Limit: Max doses should be 300 mg.day in divided doses(B,L,D)- must be taken on a full stomach,

Tramadol: Tramadol doses are usually recommended to be spaced 8 hours apart. Ibuprofen products can be used in between these doses if pain recurs early.

Every 6 hr: Should be ok since it's 6 hours between doses.

Yes: Granadilla can be taken every six hours when needed.

Yes if so directed.: You're correct. The maximum dosage of tramadol is 400 mg/day. This could be divided into 100 mg every 6 hours provided this doesn't exceed the prescribing directions on your bottle.