A member asked:

Can i take clozapine and abilify (aripiprazole) together safely?

7 doctors weighed in across 2 answers
Dr. Alvin Lin answered

Talk to your doctor: Ability (aripiprazole) is a 2nd generation antipsychotic that is indicated (approved) for use in schizophrenia & bipolar disorder as well as an adjunct in major depression. Clozapine is also a 2nd generation antipsychotic w/limited approval due to a significantly greater side effect risk. Very rarely are two medications in same class used concomitantly, and then usually only by specialists.

Answered 1/9/2021

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Drug safety.: I am not sure what the benefit would be from treating with Both Clozapine & Abilify at the same time. Is this a cross- titration? Both are antipsychotic medications used for treatment of conditions like Schizophrenia or Schizoaffective disorder. Clozapine is usually not first line due to potential side effects & monitoring requirements. Please discuss with your psychiatrist.

Answered 1/9/2021

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