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A member asked:
Dad 70 yrs old has macrocytic anemia. all else normal. bone marrow biopsy showed no cancer or mds, but failure of production of enough rbc. why?
A doctor has provided 1 answer
MDS & Macro Anemia: Causes of macrocytic anemia, other than MDS: vitamin B deficiencies, folate (folic acid) deficiency, certain drugs like zidovudine or hydroxyurea, acute leukemia, LGL leukemia, alcohol abuse, liver disease, hypothyroidism, and lab error. Additional labs include: reticulocyte count, RDW, bilirubin, and others. MDS is difficult to diagnosis and may require next generation DNA sequencing to confirm diagnosis.
Answered 9/8/2014
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Dad 70 yrs, non alchoholic. Has macrocytic anemia. Hb 10. Mcv 110. No blood loss. Bone marrow, kidney, liver, vitamins, colonscopy normal. Why anemic?
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Can it be too early to detect cancer in bone marrow biopsy? My labs show low RBC HGB 7.1 iron and is normal b12 is high. Had a bone marrow biopsy and chromosome testing done it was negative. No signs of cancer. Could it be too soon to detect cancer?
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Dad 70 yrs old has macrocytic anemia. All else normal. Hos hb went up from 9.2 to 10.2 in two month without medicine. Does that rule out mds?
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