A member asked:

When the bone marrow biopsy shows that there is production of low number of rbc but normal and no blasts, is this mds? what is unexplained anemia?

A doctor has provided 1 answer

MDS Erythroid Progen: An MDS diagnosis requires ≥ 10% of bone marrow cells showing abnormal (dysplastic) maturation. (Attached image shows erythroid dyspl). The number of cells (red, white, megakaryocytes) can be high or low. Some clarification of RBC is needed. Low number of erythroid progenitors, as the only finding, can be due to many other issues: sampling artifact, parvovirus infection, pure red cell aplasia, etc.

Answered 2/19/2015

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