A 35-year-old member asked:
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could anybody get the mthfr-a1298c gene mutation?

1 doctor answer
Dr. Su Fairchild
23 years experience Integrative Medicine
Depends: The MTHFR 1298 mutation is not uncommon, but for any given individual to have the possibility of having it, one or both of their parents must have it.
Answered on Jun 9, 2015
1
1 comment
Dr. Rhonda Simons
14 years experience Family Medicine
About 34% of the US population has at least ONE of the 1298 alleles, about 50% have at least ONE of the 677 alleles. 1298's are generally "better" to have as a single allele as they don't lead to elevated homocysteine levels or Uric acid levels-unless you are quite B12 deficient. Still recommend treatment with 15mg of L-Methylfolate, P5P, & methylcobalamin -I use a compounded one covered by insu
Sep 21, 2014

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