A 21-year-old female asked:
does heterozygous for mthfr gene mutation affect pregnancy?, and what about taking synthetic folic acid supplement?
1 doctor answer
Dr. Charles Whiting answered
26 years experience Obstetrics and Gynecology
Controversial...: Some studies have shown an association between the MTHFR gene mutation and recurrent miscarriages but this is controversial. Aside from this possibility, it doesn't cause problems with pregnancy. If you have this mutation, its a good idea to take folic acid, vitamin B-12 and Vitamen B-6. Aspirin is also sometimes recommended for women for who have had recurrent miscarriages. Best wishes!
Answered on Feb 15, 2016
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