Blood work came back on mthfr saying i was homozygous for the a1298c mutation and negative for the c677t mutation. is this anything to worry about?

Don't worry but act!: This is fairly common- about 10-15% of people have it. Many enjoy good health but it increases risk of depression, anxiety, fatigue, chronic pain and fatty liver disease. Minimize alcohol, eat a healthy diet,don't smoke, exercise and take a multivitamin with the L-5-MTHF from of folate and methylcobalamin. See https://tinyurl.com/y7zq69yw and https://draxe.com/mthfr-mutation/ for more information.

No: Dr. Baker has given you good advice. We pathologists consider this a fringe lab, with these tests being ordered by lawyer-shy practitioners. The majority of folks are told their results are bad and are offered some pricey vitamins. If you are interested in this sort of thing, get under the care of an evidence-based holist instead.