For rapidly weight lose what medicines is ore effective wellbutrin xl or topamax (topiramate), (topiramate) can i use them same time or morning wellbutrin evening topamax (topiramate)?safe?

None Indicated: These medications ARE NOT meant to be used for weight loss and ARE NOT SAFEto be used for that indication. Rapid weight loss in itself is not safe. All medications have side effects, so should only be used when absolutely needed. If you wish to loose weight eat clean and exercise. If you are significantly overweight surgery may be an option- talk to your physician.